Drugs delivered orally are often degraded in the gastrointestinal (GI) tract and the liver, lowering their efficacy.
Cutaneous drug delivery offers an alternative as it circumvents the GI tract and liver. It can also be advantageous for skin-related diseases such as skin cancers and acne. The key challenge however, is to penetrate the epidermal layers.
Several approaches are being developed for cutaneous drug delivery:
ForodermTM is a unique drug delivery platform that uses novel elongate microparticles (EMP) for the cutaneous delivery of a wide range of drug payloads including: small molecules, peptides, proteins, nanoparticles, vaccines, nutraceuticals and cosmetics.
The microparticles are not attached to any solid support, as in micro-needles, allowing application to large areas of skin. Penetration of the stratum corneum by the microparticles creates pathways for delivery. ForodermTM can also be used to deliver bioactive agents to mucosal surfaces; or added directly to existing topical formulations (solutions, gels, cream, ointments etc).
Foroderm™ has a wide range of potential applications:
A PCT application describes the composition and use of ForodermTM with national filings under examination.
We are interested in licenses and co-development activities in various application fields. We would encourage discussions regarding sponsored research programs in fields of interest with an option to license the background intellectual property.